A database of hormones and their receptors
Peptide Hormone

Search Result - 1

HMRbase accession number10388
Swiss-prot Accession numberO18641 (Sequence in FASTA format)
DescriptionPBAN-type neuropeptides precursor [Contains: Diapause hormone homolog(DH); Alpha-SG neuropeptide; Beta-SG neuropeptide; Pheromonebiosynthesis-activating neuropeptide (HeA-PBAN); Gamma-SGneuropeptide].
Source organismHelicoverpa assulta (Oriental tobacco budworm)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Noctuoidea;Noctuidae; Heliothinae; Helicoverpa.
Subcellular locationSecreted protein
Developmental StageDetected in 1-3 day old moths.
Similarity Belongs to the pyrokinin family.
Tissue SpecificitySynthesized in the suboesophageal ganglion and released in the hemolymph
Post translational modificationN/A
FunctionN/A
Protein Length194 Amino acids
Molecular weight22343
References1  PubMed abstract 9807222
2   Tang Q., Yang X., An S., Jiu M., Guo X., Ma J.; "cDNA cloning and sequence determination of the diapause hormoneneuropeptide of the oriental to tobacco budworm, Helicoverpaassulta."; Submitted (AUG-2001) to the EMBL/GenBank/DDBJ databases.
Domain NameN/A
Hormone NameBeta-SG neuropeptide
Mature Hormone SequencePKLGRSLAYDDKSFENVEFTPRL
Position of mature hormone in Pre-Hormone protein18 Residues from position (106-123)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 2

HMRbase accession number10393
Swiss-prot Accession numberO45027 (Sequence in FASTA format)
DescriptionPBAN-type neuropeptides precursor [Contains: Diapause hormone homolog(DH); Alpha-SG neuropeptide (MAB-alpha-NP); Beta-SG neuropeptide (MAB-beta-NP); Pheromone biosynthesis-activating neuropeptide (MaB-PBAN);Gamma-SG neuropeptide (MAB-gamma-NP)] (Fragment).
Source organismMamestra brassicae (Cabbage armyworm)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Noctuoidea;Noctuidae; Hadeninae; Mamestra.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the pyrokinin family.
Tissue SpecificityN/A
Post translational modification N/A
Function N/A
Protein Length155 Amino acids
Molecular weight18096
References1  PubMed abstract 9684333
Domain NameN/A
Hormone NameBeta-SG neuropeptide
Mature Hormone SequenceSLAYDDKVFENVEFTPRL
Position of mature hormone in Pre-Hormone protein18 Residues from position (67-84)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 3

HMRbase accession number10398
Swiss-prot Accession numberO76818 (Sequence in FASTA format)
DescriptionPBAN-type neuropeptides precursor [Contains: Diapause hormone homolog(DH); Alpha-SG neuropeptide; Beta-SG neuropeptide; Pheromonebiosynthesis-activating neuropeptide (AgI-PBAN); Gamma-SGneuropeptide].
Source organismAgrotis ipsilon (Black cutworm moth)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Noctuoidea;Noctuidae; Noctuinae; Agrotis.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the pyrokinin family.
Tissue SpecificityExpressed in the mandibular, maxillary and labial neuromeres of the male and female brain-suboesophageal ganglions, in the corpora cardiaca and all around the corpora allata, and at a lower level in the brain near the calyx and pedunculus of the mushroom body. Expressed in larvae and adult of both sexes
Post translational modificationN/A
FunctionN/A
Protein Length193 Amino acids
Molecular weight22014
References1  PubMed abstract 9753769
Domain NameN/A
Hormone NameBeta-SG neuropeptide
Mature Hormone SequenceSLSYEDKMFDNVEFTPRL
Position of mature hormone in Pre-Hormone protein18 Residues from position (105-122)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 4

HMRbase accession number10423
Swiss-prot Accession numberP09971 (Sequence in FASTA format)
DescriptionPBAN-type neuropeptides precursor [Contains: Diapause hormone (DH);Alpha-SG neuropeptide (Alpha-SGNP); Beta-SG neuropeptide (Beta-SGNP);Pheromone biosynthesis-activating neuropeptide I (PBAN-I) (BoM-PBAN)(Melanization and reddish coloration hormone I) (MRCH-I); Pheromonebiosynthesis-activating neuropeptide II (PBAN-II); Gamma-SGneuropeptide (Gamma-SGNP)].
Source organismBombyx mori (Silk moth)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the pyrokinin family.
Tissue SpecificitySuboesophageal ganglion
Post translational modificationN/A
Function The three SGNPS are far less active than DH in inducing diapause eggs. Beta-SGNP expressed higher pban activity than PBAN-I, but alpha- and gamma-SGNP were far less active in pheromonotropic activity
Protein Length192 Amino acids
Molecular weight22326
References1  PubMed abstract 1280417
2  PubMed abstract 8475067
3  PubMed abstract 1368584
4  PubMed abstract 2775285
5  PubMed abstract 8512566
6  PubMed abstract 3896851
Domain NameN/A
Hormone NameBeta-SG neuropeptide
Mature Hormone SequenceSVAKPQTHESLEFIPRL
Position of mature hormone in Pre-Hormone protein17 Residues from position (106-122)
ReceptorN/A
Gene ID692749      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 5

HMRbase accession number10435
Swiss-prot Accession numberP11159 (Sequence in FASTA format)
DescriptionPBAN-type neuropeptides precursor [Contains: Diapause hormone homolog(DH); Alpha-SG neuropeptide; Beta-SG neuropeptide; Pheromonebiosynthesis-activating neuropeptide (HeZ-PBAN); Gamma-SGneuropeptide].
Source organismHeliothis zea (Corn earworm) (Bollworm)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Noctuoidea;Noctuidae; Heliothinae; Helicoverpa.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the pyrokinin family.
Tissue SpecificityExpressed in the suboesophageal ganglions. Not found in corpora cardiaca, corpora allata and thoracic ganglia
Post translational modificationN/A
FunctionN/A
Protein Length194 Amino acids
Molecular weight22373
References1  PubMed abstract 8022813
2   Raina A.K., Jaffe H., Kempe T.G., Keim P., Blacher R.W., Fales H.M.,Riley C.T., Klun J.A., Ridgway R.L., Hayes D.K.; "Identification of a neuropeptide hormone that regulates sex pheromoneproduction in female moths."; Science 244:796-798(1989).
3  PubMed abstract 8791159
Domain NameN/A
Hormone NameBeta-SG neuropeptide
Mature Hormone SequenceSLAYDDKSFENVEFTPRL
Position of mature hormone in Pre-Hormone protein18 Residues from position (106-123)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated